Four-Analog Computation Based on DNA Strand Displacement
نویسندگان
چکیده
منابع مشابه
Analog Computation by DNA Strand Displacement Circuits.
DNA circuits have been widely used to develop biological computing devices because of their high programmability and versatility. Here, we propose an architecture for the systematic construction of DNA circuits for analog computation based on DNA strand displacement. The elementary gates in our architecture include addition, subtraction, and multiplication gates. The input and output of these g...
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To construct sophisticated biochemical circuits from scratch, one needs to understand how simple the building blocks can be and how robustly such circuits can scale up. Using a simple DNA reaction mechanism based on a reversible strand displacement process, we experimentally demonstrated several digital logic circuits, culminating in a four-bit square-root circuit that comprises 130 DNA strands...
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Time-varying signals are ubiquitous throughout science, and studying the high-level temporal structure of such processes is of significant practical importance. In this context, techniques from computer science such as temporal logic are a powerful tool. Temporal logic allows one to describe temporal properties of time-varying processes, e.g., the order in which particular events occur. In this...
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Chemical reaction networks (CRN’s) are important models of molecular programming that can be realized by logically reversible, and thus energy efficient, DNA strand displacement systems (DSD’s). Qian et al., [12] showed that energy efficient DSD’s are Turing-universal; however their simulation of a computation requires space (or volume) proportional to the number of steps of the computation. He...
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ژورنال
عنوان ژورنال: ACS Omega
سال: 2017
ISSN: 2470-1343,2470-1343
DOI: 10.1021/acsomega.7b00572